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How to rebuild the skin's epidermal barrier?

Updated: 4min.

Your skin is crying out for vengeance, and you are madly slapping on more and more products? Caring for irritated and sensitive skin doesn't have to be a challenge for you!

In one of the previous articles we focused on diagnosing problems with the epidermal barrier, now we will consider what ingredients may prove to be helpful in rebuilding it .

Damaged epidermal skin barrier – what does it mean?

The epidermal barrier consists of two parts:

  • layers of corneocytes , i.e. dead cells that form the stratum corneum of the epidermis,
  • intercellular cement , i.e. a binder made of a mixture of lipids that connects keratinocytes to each other.

On the surface of the skin there is a hydrolipid coat – a mixture of water and lipids, which come from the secretions of the sweat and sebaceous glands. It regulates the skin's pH , lubricates it and reduces the negative effects of harmful external factors.

If you have carefully read our article on how to recognize a damaged skin barrier , you already know that it usually manifests itself as:

  • itching, burning and redness of the skin,
  • hypersensitivity to the cosmetics used,
  • excess sebum production.

Incorrect skin care habits , as well as various individual conditions (e.g. genetic susceptibility to various skin anomalies) or diseases (such as atopic dermatitis) can weaken the epidermal barrier and lead to the above-mentioned problems.

The damaged hydrolipid coat rebuilds itself!

Every time you wash your skin , the hydrolipid coat is removed from its surface. But don't worry!

After approximately 1 to 1.5 hours, healthy skin recreates it on its own .

"Healthy" - the key word! If skin problems have a deeper basis , it may not function effectively, which may negatively affect the process of rebuilding the hydrolipid coat.

How to rebuild a damaged epidermal barrier?

Pay attention to the pH of cosmetics

Human skin has a slightly acidic reaction , which is a natural barrier and protection against the negative effects of bacteria living on the skin.

You should use cosmetics with a pH close to the natural skin pH , which is approximately 4.7 to 5.6.

Optimize your face care

Your skincare routine should be based on products and ingredients that complement each other. It's very easy to get caught up in a shopping frenzy, especially when new cosmetics are appearing on the market. You know how it works: "if it helped my friend, maybe it will help me too?" This way, your wallet loses weight and your skin is overstimulated, which can negatively affect its condition.

Paulina Pomaska ​​wrote about what elements are essential in a basic facial care routine. I encourage you to read this article !

What ingredients are desirable in the care of irritated skin?

Active ingredients

Active substances are those ingredients of cosmetics that determine their target effect (for example, moisturizing).

  • Niacinamide – a derivative of vitamin B3, also known as vitamin PP. Improves the skin barrier function by increasing the amount of ceramides and intercellular lipids. Studies have shown that applying a preparation with niacinamide twice a day can reduce skin inflammation , limit transepidermal water loss and increase the thickness of the stratum corneum .
  • Centella asiatica application of cosmetics containing its extract has been shown to increase skin hydration (i.e. water content in the stratum corneum) and reduce transepidermal water loss and the intensity of erythema . Due to its anti-inflammatory effects, it can alleviate symptoms resulting from damage to the epidermal barrier .
  • Squalane (stable derivative of squalene – an element of the lipid coat) – has strong moisturizing properties, but does not leave a greasy film on the skin. It also effectively retains moisture in the stratum corneum of the epidermis, minimizing transepidermal water loss.

Occlusive moisturizers

These are substances that create a barrier on the skin surface that prevents excessive transepidermal water loss. This protection allows the water content in the stratum corneum of the epidermis to be replenished through its deeper layers and the dermis.

Occlusive moisturizers include:

  • Vaseline – according to experts, it can block up to 99% of transepidermal water loss,
  • vegetable oils (e.g. coconut or castor),
  • sterols (including cholesterol, ceramides).

Humectants

These are compounds that bind water molecules and attract them from the deeper layers of the epidermis and dermis. Some humectants can therefore increase transepidermal water loss, which is why it is worth using occlusive moisturizers at the same time.

Alpha-hydroxy acids (AHAs) are a group of glycolic and lactic acids. They are effective humectants that cause exfoliation of the epidermal layers and improve the skin's barrier function by increasing the level of ceramides. Lactic acid at a concentration of up to 12% is a popular tool in the fight against dry skin or so-called ichthyosis.

Another popular humectant is, for example, glycerin .

Emulsifiers

This is another group of substances commonly found in moisturizing preparations. They prevent the separation of cosmetic ingredients, which (under normal conditions) were not able to chemically combine with each other. Thanks to emulsifiers, the resulting preparation (i.e. emulsion ) is stable and suitably viscous.

These include, among others:

  • fatty acids (e.g. stearic acid),
  • higher alcohols (e.g. cetyl alcohol),
  • cholesterol ,
  • lanolin .

Attention, interesting fact! Some of the occlusive moisturizing substances also have emulsifying properties ! For example, the substances mentioned above exhibit the action characteristic of both groups of ingredients.

Vitamins

Niacinamide is a derivative of vitamin B3. It is also known as vitamin PP. It improves the function of the epidermal barrier by increasing the amount of ceramides and intercellular lipids. Studies have shown that applying a preparation with niacinamide twice a day can reduce skin inflammation, limit transepidermal water loss and increase the thickness of the stratum corneum of the epidermis.

Vitamin C has a very wide range of clinical applications: from anti-aging to photoprotective (protecting against the negative effects of solar radiation). It is also necessary for proper collagen synthesis.

Remember: the best treatment tailored to the specific needs of your skin should be offered to you by a specialist. So don't hesitate to consult a beautician if you experience any unwanted skin ailments!

And let our articles be a nice guide for you. Cheers!

  • Arc, K. Pytkowska, A. Ratz-Łyko, Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract , "Indian Journal of Pharmaceutical Sciences" 2016, vol. 78, i. 1, p. 27-33, https://pubmed.ncbi.nlm.nih.gov/27168678/ [accessed on November 21, 2022].
  • Arribas-Lopez, T. Kochhar, O. Ojo et al., A Systematic Review of The Effect of Centella asiatica on Wound Healing , "International Journal of Environmental Research and Public Health" 2022, vol. 19, i. 6, p. 3266, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8956065/#!po=18.8312 [accessed on November 21, 2022].
  • JQ Del Rosso, Repair and Maintenance of the Epidermal Barrier in Patients Diagnosed with Atopic Dermatitis , "The Journal of Clinical and Aesthetic Dermatology" 2011, vol. 4, i. 6, p. 45-55, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140899/ [accessed on November 21, 2022].
  • Harwood, K. Krishnamurty, A. Nassereddin, Moisturizers , "StatPearls Publishing", https://www.ncbi.nlm.nih.gov/books/NBK545171/ [accessed 21.11.2022].
  • SK Kim, F. Karadeniz, Biological Importance and Applications of Squalene and Squalane , "Advances in Food and Nutrition Research" 2012, vol. 65, p. 223-233, https://pubmed.ncbi.nlm.nih.gov/22361190/ [accessed on November 21, 2022].
  • Mohammed, JM Crowther, PJ Matts et al., Influence of niacinamide containing formulations on the molecular and biophysical properties of the stratum corneum , "International Journal of Pharmaceutics" 2013, vol. 441, i. 1-2, p. 192-201, https://pubmed.ncbi.nlm.nih.gov/23220080/ [accessed on November 21, 2022].
  • Park, Role of Micronutrients in Skin Health and Function , "Biomolecules & Therapeutics" 2015, vol. 23, i. 3, p. 207-217, https://www.biomolther.org/journal/view.html?uid=517&vmd=Full [accessed on November 21, 2022].
  • Płocica, B. Tal-Figiel, W. Figiel, Correlation between rheological studies and organoleptic cosmetic emulsions with lanolin-natural emulsifier , "Czasopismo Techniczne. Chemia" 2013, i. 1, p. 61-68.
  • Purnamawati, N. Indrastuti, R. Danarti, T. Saefudin, The Role of Moisturizers in Addressing Various Kinds of Dermatitis: A Review , "Clinical Medicine & Research" 2017, vol. 15, i. 3-4, p. 75-87, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849435/ [accessed on November 21, 2022].
  • N. Molinero, L. Ruiz, B. Sánchez et al., Intestinal Bacteria Interplay With Bile and Cholesterol Metabolism: Implications on Host Physiology , "Frontiers in Physiology" 2019, vol. 10, p. 185, https://pubmed.ncbi.nlm.nih.gov/30923502/ [accessed on November 21, 2022].
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    Created at: 06/12/2022

    Updated at: 22/02/2023

    Author

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